Paul S. Baker, M.D., and Gary C. Brown from the Retina Service, Wills Eye Institute, Jefferson Medical College, in Philadelphia, Pennsylvania, wrote an article “Stem-cell therapy in retinal disease” for Current Opinion in Ophthalmology 2009; 20:175-181. They stated on page 178 of the article:
Although some studies were unable to demonstrate any positive effect on vision, other patients transplanted with fetal retinal sheets showed improved visual acuity over time (up to 6 years) [57**, 58].
The unprecedented double starring of our article in the reference meant “of outstanding interest.”
Papers of particular interest, published within the annual period of review, have been highlighted as:
*of special interest
**of outstanding interest
Additional references related to this topic can also be found in the Current World Literature section in this issue (p. 226).
Radtke ND, Aramant RB, Petry HM, et al. Vision improvement in retinal degeneration patients by implantation of retina together with retinal pigment epithelium. Am J Ophthalmol 2008; 146:172-182.
This study demonstrates the safety and clinical benefit of retina RPE grafts in human subjects with retinal degeneration. Visual improvement was observed in seven of ten patients (three retinitis pigmentosa and four AMD).
Radtke ND, Aramant RB, Seiler MJ, et al. Vision change after sheet transplant of fetal retina with retinal pigment epithelium to a patient with retinitis pigmentosa. Arch Ophthalmol 2004; 122:1159-1165.
We were honored that our work received such recognition from these esteemed professors.