Cone-rod dystrophy is characterized by early loss of visual acuity and color vision, with subsequent progressive peripheral loss of visual field. In the early stage of the disease, before peripheral field defects or peripheral abnormalities are apparent, a diagnosis of macular or cone dystrophy may be made. Peripheral retinal bone pigmentation in later disease may resemble that seen in classical retinitis pigmentosa.
Recent molecular genetic studies have identified 10 different genomic regions, each of which contains a CRD causing gene.
Autosomal dominant, recessive and x-linked patterns have been described.
Research efforts are being made to attempt to try to treat this condition.